Organooxygen compounds
Medchemexpress LLC Fadrozole hydrochloride | 102676-31-3 | 99.9% | C14H14ClN3 | 1 ML
Fadrozole hydrochloride (CGS 16949A) is a potent, selective, and nonsteroidal aromatase inhibitor that effectively inhibits estrogen production. It is intended for research use only and not for patient use.
- Potent and selective aromatase inhibitor with an IC50 of 6.4 nM.
- Inhibits estrogen production in hamster ovarian slices with an IC50 of 0.03 μM.
- Can suppress the synthesis of other cytochrome P-450 dependent steroids at higher doses.
- Prevents the development of spontaneous mammary neoplasms in female rats.
- Slows the development of pituitary pars distalis adenomas.
- Reduces the incidence of spontaneous hepatocellular tumors.
- Reduces parasite burden in male and female mice by 70%.
Medchemexpress LLC BMY-14802 hydrochloride | 105565-55-7 | 98.0% | 384.85 | 500 UG
BMY-14802 hydrochloride (BMY-14802-1) is a selective and orally active sigma receptor antagonist with an IC50 of 112 nM. It is also a 5-HT1A and adrenergic α1 receptors agonist. BMY-14802 hydrochloride has antipsychotic effects.
- Selective and orally active sigma receptor antagonist.
- Acts as a 5-HT1A and adrenergic α1 receptor agonist.
- Exhibits antipsychotic effects.
Medchemexpress LLC Guanabenz hydrochloride | 23113-43-1 | 99.9% | 100 MG
Guanabenz hydrochloride is an orally active α-2-adrenoceptor agonist. It exhibits antihypertensive and antiparasitic activity, interferes with ER stress-signalling, and offers protective effects in cardiac myocytes. It is also used for research related to high blood pressure.
- Orally active α-2-adrenoceptor agonist
- Exhibits antihypertensive activity
- Possesses antiparasitic activity
- Interferes with ER stress-signaling
- Offers protective effects in cardiac myocytes
- Used for research related to high blood pressure
Medchemexpress LLC Clemizole hydrochloride | 1163-36-6 | 99.99% | 362.30 | 100 MG
Clemizole hydrochloride is an H1 histamine receptor antagonist that substantially inhibits HCV replication and is an inhibitor of the TRPC5 channel. It has an IC50 of 24 nM for RNA binding by NS4B and an EC50 of 8 μM for viral replication. For research use only.
- H1 histamine receptor antagonist.
- Substantially inhibits HCV replication.
- Inhibitor of TRPC5 channel.
- EC50 of 8 μM for viral replication.
- IC50 of 24 nM for RNA binding by NS4B.
- Inhibits HCV RNA replication in cell culture mediated by suppression of NS4B's RNA binding with little toxicity for the host cell.
- Efficiently blocks TRPC5 currents and Ca2+ entry in the low micromolar range (IC50=1.0-1.3 μM).
- Exhibits six-fold selectivity for TRPC5 over TRPC4β (IC50=6.4 μM) and almost 10-fold selectivity over TRPC3 (IC50=9.1 μM) and TRPC6 (IC50=11.3 μM).
Medchemexpress LLC Glafenine (hydrochloride) | 65513-72-6 | 10 MM 1 ML
Glafenine (hydrochloride) | 65513-72-6 | 10 MM 1 ML
Medchemexpress LLC Belotecan hydrochloride | 213819-48-8 | MFCD07772313 | 99.0% | C25H28ClN3O4 | 10MG
Belotecan hydrochloride is a synthetic camptothecin derivative that acts as a potent topoisomerase I inhibitor used for preclinical oncology research. It is supplied as a solid powder and as a DMSO solution for laboratory studies, and is used to investigate DNA damage, cell cycle effects, and anticancer activity in cell-based and biochemical assays.
- Potent topoisomerase I inhibition for anticancer research.
- Available as solid powder and as a 10 mM solution in DMSO.
- High reported purity suitable for preclinical assays.
- White to yellow solid appearance facilitating visual inspection.
- Supplied with documentation such as COA and SDS for quality and safety.
Medchemexpress LLC Deterenol hydrochloride | 23239-36-3 | MFCD28898982 | 99.7% | 231.72 g/mol | C11H18ClNO2 | 25 MG
Deterenol hydrochloride is the hydrochloride salt of deterenol, a selective beta-adrenergic agonist used as a research reagent. Provided as a solid with high purity, it is intended for in vitro and in vivo pharmacology studies involving beta-adrenergic receptors and cardiovascular response assessment.
- Selective beta-adrenergic agonist activity.
- High purity suitable for research applications.
- Hydrochloride salt form for improved stability and handling.
- Common use in receptor pharmacology and cardiovascular studies.
- Molecular formula C11H18ClNO2; molecular weight 231.72 g/mol.
- CAS number 23239-36-3 for unambiguous identification.
Medchemexpress LLC Pumosetrag hydrochloride | 194093-42-0 | MFCD00939557 | 99.8% | 339.84 g/mol | C15H18ClN3O2S | 10 MG
Pumosetrag hydrochloride is an orally active, small-molecule partial agonist of the 5-HT3 receptor investigated for treatment of irritable bowel syndrome and gastroesophageal reflux disease. Supplied as a high-purity white to off-white solid for laboratory research (for research use only).
- Acts as a partial agonist at 5-HT3 receptors.
- Investigated for irritable bowel syndrome and gastroesophageal reflux disease.
- Supplied as a white to off-white solid with high purity.
- Molecular weight 339.84 g/mol; formula C15H18ClN3O2S.
- Available in small laboratory pack sizes, including 10 mg.
- Store sealed at 4°C; in solvent store at -80°C (6 months) or -20°C (1 month).
- For research use only; not for human or clinical use.
Medchemexpress LLC Noscapine (hydrochloride) | 912-60-7 | 99.9% | 449.88 | 1 G
Noscapine (hydrochloride) is an orally active phthalideisoquinoline alkaloid with potent antitussive properties. It activates sigma opioid receptors and acts as a non-competitive Bradykinin inhibitor. This compound also disrupts microtubule dynamics, induces mitotic arrest and apoptosis.
- Orally active phthalideisoquinoline alkaloid
- Potent antitussive properties
- Activates sigma opioid receptors and acts as a non-competitive Bradykinin inhibitor
- Disrupts microtubule dynamics, induces mitotic arrest and apoptosis
- Exhibits anticancer, neuroprotective, and anti-inflammatory activities
- Can cross the blood-brain barrier
eMolecules 485-47-2 | NINHYDRIN | AstaTech | MFCD00003791 | 178.143 | C9H6O4 | 95.000 | OC1(O)C(=O)c2ccccc2C1=O | 25g | 392639080
NINHYDRIN | AstaTech | 485-47-2 | MFCD00003791 | 178.143 | C9H6O4 | 95.000 | OC1(O)C(=O)c2ccccc2C1=O | 25g | 392639080
eMolecules 29671-92-9 | Chloroformamidine hydrochloride | Ochem Incorporation | MFCD00035527 | 114.960 | CH4Cl2N2 | 98.000 | Cl.NC(Cl)=N | 5g | 773154939
Chloroformamidine hydrochloride | Ochem Incorporation | 29671-92-9 | MFCD00035527 | 114.960 | CH4Cl2N2 | 98.000 | Cl.NC(Cl)=N | 5g | 773154939